Instructions for Leopard, OSX 10.5 are here
Setting up Wordpress on my home computer was supposed to be painless but did not turn out that way at all.
If you are installing Wordpress on OSX and everything is set up and working but Wordpress will not talk to the server skip right to step 10 on the instruction page. Or better go to MySQL Reference for OSX there are a few solutions on that page. I took the easy one.
Another great set of instructions for setting up Wordpress on OSX is Installing WordPress on Tiger. It is a very easy to follow set of instructions. I had to go look up a few things that weren’t covered there. I hope I covered everything in my directions.